The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
The N-linked oligomannose glycans of HIV gp120 are a target for both microbicide and vaccine design. The extent of cross-clade conservation of HIV oligomannose glycans is therefore a critical consideration for the development of HIV prophylaxes. We measured the oligomannose content of virion-associa...
Main Authors: | Bonomelli, C, Doores, K, Dunlop, D, Thaney, V, Dwek, R, Burton, D, Crispin, M, Scanlan, C |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2011
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