The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.

The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.

The N-linked oligomannose glycans of HIV gp120 are a target for both microbicide and vaccine design. The extent of cross-clade conservation of HIV oligomannose glycans is therefore a critical consideration for the development of HIV prophylaxes. We measured the oligomannose content of virion-associa...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Bonomelli, C, Doores, K, Dunlop, D, Thaney, V, Dwek, R, Burton, D, Crispin, M, Scanlan, C
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Public Library of Science 2011

Ижил төстэй зүйлс

Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens
-н: Doores, K, зэрэг
Хэвлэсэн: (2010)

Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans.
-н: Dunlop, D, зэрэг
Хэвлэсэн: (2010)

Trimeric HIV-1-env structures define glycan shields from clades A, B, and G
-н: Stewart-Jones, G, зэрэг
Хэвлэсэн: (2016)

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
-н: Doores, K, зэрэг
Хэвлэсэн: (2010)

Antibodies expose multiple weaknesses in the glycan shield of HIV.
-н: Crispin, M, зэрэг
Хэвлэсэн: (2013)

Antibodies expose multiple weaknesses in the glycan shield of HIV.
-н: Crispin, M, зэрэг
Хэвлэсэн: (2013)

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
-н: Pejchal, R, зэрэг
Хэвлэсэн: (2011)

Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies.
-н: Pritchard, L, зэрэг
Хэвлэсэн: (2015)

Architecture of the HIV-1 glycan shield
-н: Pritchard, L
Хэвлэсэн: (2014)

Fine structure of the HIV-1 glycan shield
-н: Behrens, A
Хэвлэсэн: (2017)

Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.
-н: Radcliffe, C, зэрэг
Хэвлэсэн: (2007)

A potential survival strategy for human follicular lymphoma cells involving oligomannose glycans in the antigen-binding site
-н: Radcliffe, C, зэрэг
Хэвлэсэн: (2005)

Fine structure of the HIV-1 glycan shield - Supplementary information
-н: Behrens, A
Хэвлэсэн: (2017)

The impact of sequence diversity on the glycan shield of HIV-1 immunogens
-н: Seabright, GE
Хэвлэсэн: (2019)

The tetrameric plant lectin BanLec neutralizes HIV through bidentate binding to specific viral glycans.
-н: Hopper, J, зэрэг
Хэвлэсэн: (2017)

An endoglycosidase with alternative glycan specificity allows broadened glycoprotein remodelling.
-н: Goodfellow, J, зэрэг
Хэвлэсэн: (2012)

Targeting host-derived glycans on enveloped viruses for antibody-based vaccine design
-н: Crispin, M, зэрэг
Хэвлэсэн: (2015)

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
-н: Watanabe, Y, зэрэг
Хэвлэсэн: (2020)

Mapping the glycan shields of enveloped viruses
-н: Watanabe, Y
Хэвлэсэн: (2020)

Cell- and protein-directed glycosylation of native cleaved HIV-1 envelope
-н: Pritchard, L, зэрэг
Хэвлэсэн: (2015)

Completeness of HIV-1 envelope glycan shield at transmission determines neutralization breadth
-н: Wagh, K, зэрэг
Хэвлэсэн: (2018)

HIV-1 glycan density drives the persistence of the mannose patch within an infected individual
-н: Coss, K, зэрэг
Хэвлэсэн: (2016)

Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.
-н: Scanlan, C, зэрэг
Хэвлэсэн: (2007)

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies
-н: McCoy, Laura E., зэрэг
Хэвлэсэн: (2016)

The HIV-1 Glycan Shield: Strategically Placed Kinks in the Armor Improve Antigen Design
-н: Karsten, Christina Beatrice, зэрэг
Хэвлэсэн: (2017)

Yeast mannan genetics controls the molecular specificity of anti-carbohydrate antibodies cross-reactive to the HIV envelope
-н: Dunlop, D, зэрэг
Хэвлэсэн: (2009)

Structure of the Lassa virus glycan shield provides a model for immunological resistance
-н: Watanabe, Y, зэрэг
Хэвлэсэн: (2018)

The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin.
-н: Arnold, J, зэрэг
Хэвлэсэн: (2004)

Glycan microheterogeneity at the PGT135 antibody recognition site on HIV-1 gp120 reveals a molecular mechanism for neutralization resistance.
-н: Pritchard, L, зэрэг
Хэвлэсэн: (2015)

Glycan–protein interactions in viral pathogenesis
-н: Raman, Rahul, зэрэг
Хэвлэсэн: (2018)

HIV T cell vaccines, the importance of clades.
-н: McMichael, A, зэрэг
Хэвлэсэн: (2002)

Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein
-н: Crispin, M, зэрэг
Хэвлэсэн: (2016)

Arenavirus glycan shield promotes neutralizing antibody evasion and protracted infection.
-н: Sommerstein, R, зэрэг
Хэвлэсэн: (2015)

Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
-н: Dunlop, D, зэрэг
Хэвлэсэн: (2008)

Antigenic mimicry of the HIV envelope by AIDS-Associated pathogens
-н: Dunlop, D, зэрэг
Хэвлэсэн: (2008)

HLA-B1302 is associated with viral control in clade CRF01_AE HIV-1 infection in Thailand
-н: Hempel, U, зэрэг
Хэвлэсэн: (2009)

A 'non-self' mimic of the natural epitope of anti-HIV antibody 2G12 shows enhanced antigenicity
-н: Doores, K, зэрэг
Хэвлэсэн: (2009)

Ion mobility mass spectrometry for ion recovery and clean-up of MS and MS/MS spectra obtained from low abundance viral samples
-н: Harvey, DJ, зэрэг
Хэвлэсэн: (2015)

Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis
-н: Bowden, T, зэрэг
Хэвлэсэн: (2012)

Phylodynamics of the HIV-1 CRF02_AG clade in Cameroon.
-н: Faria, N, зэрэг
Хэвлэсэн: (2012)