The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.
The N-linked oligomannose glycans of HIV gp120 are a target for both microbicide and vaccine design. The extent of cross-clade conservation of HIV oligomannose glycans is therefore a critical consideration for the development of HIV prophylaxes. We measured the oligomannose content of virion-associa...
| Main Authors: | , , , , , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
Public Library of Science
2011
|