CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells.

Graft-versus-host disease (GVHD) is a major cause of mortality and morbidity after allogeneic bone marrow transplantation, but can be avoided by removing T lymphocytes from the donor bone marrow. However, T cell depletion increases the risk of graft rejection. In this study, two strategies are used...

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Bibliographic Details
Main Authors: Hale, G, Jacobs, P, Wood, L, Fibbe, W, Barge, R, Novitzky, N, Toit, C, Abrahams, L, Thomas, V, Bunjes, D, Duncker, C, Wiesneth, M, Selleslag, D, Hidajat, M, Starobinski, M, Bird, P, Waldmann, H
Format: Journal article
Language:English
Published: 2000