On the evolution of protein folds: are similar motifs in different protein folds the result of convergence, insertion, or relics of an ancient peptide world?

This paper presents and discusses evidence suggesting how the diversity of domain folds in existence today might have evolved from peptide ancestors. We apply a structure similarity detection method to detect instances where localized regions of different protein folds contain highly similar sequenc...

Full description

Bibliographic Details
Main Authors: Lupas, A, Ponting, C, Russell, R
Format: Journal article
Language:English
Published: 2001