Dosage sensitivity shapes the evolution of copy-number varied regions
Dosage sensitivity is an important evolutionary force which impacts on gene dispensability and duplicability. The newly available data on human copy-number variation (CNV) allow an analysis of the most recent and ongoing evolution. Provided that heterozygous gene deletions and duplications actually...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Public Library of Science
2010
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