Development of biochemical tools to characterise human H3K27 histone demethylase JmjD3

<p>Covalent modifications of histone tails play essential roles in mediating chromatin structure and epigenetic regulation. JmjD3 is a JumonjiC domain containing histone demethylase, belongs to the KDM6 subfamily, and catalyses the removal of methyl groups on methylated lysine 27 on histone 3...

Full description

Bibliographic Details
Main Author: Che, KH
Other Authors: Oppermann, U
Format: Thesis
Language:English
Published: 2013
Subjects: