Isoforms of U1-70k control subunit dynamics in the human spliceosomal U1 snRNP.

Most human protein-encoding genes contain multiple exons that are spliced together, frequently in alternative arrangements, by the spliceosome. It is established that U1 snRNP is an essential component of the spliceosome, in human consisting of RNA and ten proteins, several of which are post-transla...

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Detalhes bibliográficos
Principais autores: Hernandez, H, Makarova, O, Makarov, E, Morgner, N, Muto, Y, Krummel, D, Robinson, C
Formato: Journal article
Idioma:English
Publicado em: Public Library of Science 2009