Isoforms of U1-70k control subunit dynamics in the human spliceosomal U1 snRNP.
Most human protein-encoding genes contain multiple exons that are spliced together, frequently in alternative arrangements, by the spliceosome. It is established that U1 snRNP is an essential component of the spliceosome, in human consisting of RNA and ten proteins, several of which are post-transla...
Main Authors: | Hernandez, H, Makarova, O, Makarov, E, Morgner, N, Muto, Y, Krummel, D, Robinson, C |
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Format: | Journal article |
Jezik: | English |
Izdano: |
Public Library of Science
2009
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