Beta-cell hubs maintain Ca2+ oscillations in human and mouse islet simulations
Islet β-cells are responsible for secreting all circulating insulin in response to rising plasma glucose concentrations. These cells are a phenotypically diverse population that express great functional heterogeneity. In mice, certain β-cells (termed ‘hubs’) have been shown to be crucial for dictati...
| Main Authors: | , , , , , |
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| 格式: | Journal article |
| 出版: |
Taylor and Francis
2018
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