Beta-cell hubs maintain Ca2+ oscillations in human and mouse islet simulations
Islet β-cells are responsible for secreting all circulating insulin in response to rising plasma glucose concentrations. These cells are a phenotypically diverse population that express great functional heterogeneity. In mice, certain β-cells (termed ‘hubs’) have been shown to be crucial for dictati...
Main Authors: | Lei, C, Kellard, J, Hara, M, Johnson, J, Rodriguez, B, Briant, L |
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Format: | Journal article |
Udgivet: |
Taylor and Francis
2018
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