Beta-cell hubs maintain Ca2+ oscillations in human and mouse islet simulations
Islet β-cells are responsible for secreting all circulating insulin in response to rising plasma glucose concentrations. These cells are a phenotypically diverse population that express great functional heterogeneity. In mice, certain β-cells (termed ‘hubs’) have been shown to be crucial for dictati...
| Autori principali: | , , , , , |
|---|---|
| Natura: | Journal article |
| Pubblicazione: |
Taylor and Francis
2018
|