Beta-cell hubs maintain Ca2+ oscillations in human and mouse islet simulations

Islet β-cells are responsible for secreting all circulating insulin in response to rising plasma glucose concentrations. These cells are a phenotypically diverse population that express great functional heterogeneity. In mice, certain β-cells (termed ‘hubs’) have been shown to be crucial for dictati...

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Detalles Bibliográficos
Main Authors: Lei, C, Kellard, J, Hara, M, Johnson, J, Rodriguez, B, Briant, L
Formato: Journal article
Publicado: Taylor and Francis 2018