The imidazoacridinone C-1311 induces p53-dependent senescence or p53-independent apoptosis and sensitizes cancer cells to radiation

C-1311 is a small molecule, which has shown promise in a number of pre-clinical and clinical studies. However, the biological response to C-1311 exposure is complicated and has been reported to involve a number of cell fates. Here, we investigated the molecular signaling which determines the respons...

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Bibliographic Details
Main Authors: Skwarska, A, Ramachandran, S, Dobrynin, G, Leszczynska, K, Hammond, E
Format: Journal article
Published: Impact Journals 2017