PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder

PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder

<p>Proliferating cell nuclear antigen (PCNA) is an essential cofactor for DNA replication and repair. The toroidal structure of a PCNA trimer makes it a sliding clamp protein, which utilizes its interdomain connecting loop (IDCL) interacting with PIP-box containing proteins to recruit these cl...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Wang, L
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2019
Ábhair:	Cell biology DNA repair DNA replication

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