Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.

To this day, a significant proportion of the human genome remains devoid of functional characterization. In this study, we present evidence that the previously functionally uncharacterized product of the human DHRS10 gene is endowed with 17beta-HSD (17beta-hydroxysteroid dehydrogenase) activity. 17b...

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Bibliographic Details
Main Authors: Lukacik, P, Keller, B, Bunkoczi, G, Kavanagh, K, Lee, W, Adamski, J, Oppermann, U
Format: Journal article
Language:English
Published: 2007
Subjects: