Multi-component polymeric system for tumour cell-specific gene delivery using a universal bungarotoxin linker.

PURPOSE: A new universal tool for specific, non-covalent and non-destructive attachment of a recombinant antibody fragment to a polymer-modified adenovirus has been utilised to regulate the tropism of adenoviral gene delivery vector. METHODS: We have prepared a multivalent reactive N-(2-hydroxypropy...

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Bibliographic Details
Main Authors: Willemsen, R, Pechar, M, Carlisle, R, Schooten, E, Pola, R, Thompson, A, Seymour, L, Ulbrich, K
Format: Journal article
Language:English
Published: 2010