Vav regulates peptide-specific apoptosis in thymocytes.

The protooncogene Vav functions as a GDP/GTP exchange factor (GEF) for Rho-like small GTPases involved in cytoskeletal reorganization and cytokine production in T cells. Gene-targeted mice lacking Vav have a severe defect in positive and negative selection of T cell antigen receptor transgenic thymo...

詳細記述

書誌詳細
主要な著者: Kong, Y, Fischer, K, Bachmann, M, Mariathasan, S, Kozieradzki, I, Nghiem, M, Bouchard, D, Bernstein, A, Ohashi, P, Penninger, J
フォーマット: Journal article
言語:English
出版事項: 1998