Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection

It is well established that antibiotic treatment selects for resistance, but the dynamics of this process during infections are poorly understood. Here we map the responses of Pseudomonas aeruginosa to treatment in high definition during a lung infection of a single ICU patient. Host immunity and an...

Full description

Bibliographic Details
Main Authors: Wheatley, R, Diaz Caballero, J, Kapel, N, Jangir, P, Hedge, J, Quinn, A, Maclean, RC, Et al.
Format: Journal article
Language:English
Published: Nature Research 2021