Trimethoprim-sulfamethoxazole versus trimethoprimsulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): A multicentre, double-blind, non-inferiority, randomised controlled trial

Background Melioidosis, an infectious disease caused by the Gram-negative bacillus Burkholderia pseudomallei, is difficult to cure. Antimicrobial treatment comprises intravenous drugs for at least 10 days, followed by oral drugs for at least 12 weeks. The standard oral regimen based on trial evidenc...

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Bibliographic Details
Main Authors: Chetchotisakd, P, Anunnatsiri, S, Mootsikapun, P, Wongrattanacheewin, S, Chierakul, W, Wuthiekanun, V, Chantratita, N, Thaipadungpanit, J, Day, N, Limmathurotsakul, D, Peacock, S, Chaowagul, W, Phimda, K, Phiphitaporn, S, Chaisuksant, S, Susaengrat, W, Pilaikul, J, Toondee, C, Thinkhamrop, B
Format: Journal article
Published: 2014