A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas.

Pheochromocytomas are neural crest-derived tumors that arise from inherited or sporadic mutations in at least six independent genes. The proteins encoded by these multiple genes regulate distinct functions. We show here a functional link between tumors with VHL mutations and those with disruption of...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Dahia, P, Ross, K, Wright, M, Hayashida, C, Santagata, S, Barontini, M, Kung, A, Sanso, G, Powers, J, Tischler, A, Hodin, R, Heitritter, S, Moore, F, Dluhy, R, Sosa, J, Ocal, I, Benn, D, Marsh, D, Robinson, BG, Schneider, K, Garber, J, Arum, S, Korbonits, M, Grossman, A, Pigny, P, Toledo, S, Nosé, V, Li, C, Stiles, C
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Public Library of Science 2005

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas.

Ижил төстэй зүйлс