The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.

Integrins are cell surface receptors crucial for cell migration and adhesion. They are activated by interactions of the talin head domain with the membrane surface and the integrin β cytoplasmic tail. Here, we use coarse-grained molecular dynamic simulations and nuclear magnetic resonance spectrosco...

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Bibliographic Details
Main Authors: Kalli, A, Wegener, K, Goult, B, Anthis, N, Campbell, I, Sansom, MS
Format: Journal article
Language:English
Published: 2010