The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.
Integrins are cell surface receptors crucial for cell migration and adhesion. They are activated by interactions of the talin head domain with the membrane surface and the integrin β cytoplasmic tail. Here, we use coarse-grained molecular dynamic simulations and nuclear magnetic resonance spectrosco...
Κύριοι συγγραφείς: | Kalli, A, Wegener, K, Goult, B, Anthis, N, Campbell, I, Sansom, MS |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2010
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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The structure of an interdomain complex that regulates talin activity.
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A helix heterodimer in a lipid bilayer: prediction of the structure of an integrin transmembrane domain via multiscale simulations.
ανά: Kalli, A, κ.ά.
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