Testing the role of multicopy plasmids in the evolution of antibiotic resistance

Multicopy plasmids are extremely abundant in prokaryotes but their role in bacterial evolution remains poorly understood. We recently showed that the increase in gene copy number per cell provided by multicopy plasmids could accelerate the evolution of plasmid-encoded genes. In this work, we present...

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Bibliographic Details
Main Authors: Escudero, J, MacLean, R, San Millan, A
Format: Journal article
Published: Journal of Visualized Experiments 2018