Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease.
Susceptibility to coeliac disease involves HLA and non-HLA-linked genes. The CTLA4/CD28 gene region encodes immune regulatory T-cell surface molecules and is a strong candidate as a susceptibility locus. We evaluated CTLA4/CD28 in coeliac disease by genetic linkage and association and combined our f...
Հիմնական հեղինակներ: | , , , , , , , , , , , , , , , , , , , , |
---|---|
Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2002
|