A pre-initiation complex at the 3'-end of genes drives antisense transcription independent of divergent sense transcription.

The precise nature of antisense transcripts in eukaryotes such as Saccharomyces cerevisiae remains elusive. Here we show that the 3' regions of genes possess a promoter architecture, including a pre-initiation complex (PIC), which mirrors that at the 5' region and which is much more pronou...

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Bibliographic Details
Main Authors: Murray, S, Serra Barros, A, Brown, D, Dudek, P, Ayling, J, Mellor, J
Format: Journal article
Language:English
Published: Oxford University Press 2012