A pre-initiation complex at the 3'-end of genes drives antisense transcription independent of divergent sense transcription.
The precise nature of antisense transcripts in eukaryotes such as Saccharomyces cerevisiae remains elusive. Here we show that the 3' regions of genes possess a promoter architecture, including a pre-initiation complex (PIC), which mirrors that at the 5' region and which is much more pronou...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2012
|