CDX1 is an important molecular mediator of Barrett's metaplasia.

The molecular pathogenesis of Barrett's metaplasia (BM) of the esophagus is poorly understood. The change to an intestinal phenotype occurs on a background of esophagitis due to refluxing acid and bile. CDX1, an important regulator of normal intestinal development, was studied as a potential ke...

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Bibliographic Details
Main Authors: Wong, N, Wilding, J, Bartlett, S, Liu, Y, Warren, B, Piris, J, Maynard, N, Marshall, R, Bodmer, W
Format: Journal article
Language:English
Published: 2005