Antiviral inhibitory capacity of CD8+ T cells predicts the rate of CD4+ T-cell decline in HIV-1 infection.

BACKGROUND: Rare human immunodeficiency virus type 1 (HIV-1)-infected individuals who maintain control of viremia without therapy show potent CD8+ T-cell-mediated suppression of viral replication in vitro. Whether this is a determinant of the rate of disease progression in viremic individuals is unk...

詳細記述

書誌詳細
主要な著者: Yang, H, Wu, H, Hancock, G, Clutton, G, Sande, N, Xu, X, Yan, H, Huang, X, Angus, B, Kuldanek, K, Fidler, S, Denny, T, Birks, J, McMichael, A, Dorrell, L
フォーマット: Journal article
言語:English
出版事項: 2012