Breadth of anti-merozoite antibody responses is associated with the genetic diversity of asymptomatic Plasmodium falciparum infections and protection against clinical malaria.

BACKGROUND: Elucidating the mechanisms of naturally acquired immunity to Plasmodium falciparum infections would be highly valuable for malaria vaccine development. Asymptomatic multiclonal infections have been shown to predict protection from clinical malaria in a transmission-dependent manner, but...

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Bibliographic Details
Main Authors: Rono, J, Osier, F, Olsson, D, Montgomery, S, Mhoja, L, Rooth, I, Marsh, K, Färnert, A
Format: Journal article
Language:English
Published: 2013