The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

The RNA-dependent RNA polymerase VP1 of infectious pancreatic necrosis virus (IPNV) is a single polypeptide responsible for both viral RNA transcription and genome replication. Sequence analysis identifies IPNV VP1 as having an unusual active site topology. We have purified, crystallized and solved...

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Bibliographic Details
Main Authors: Graham, S, Sarin, L, Bahar, M, Myers, R, Stuart, D, Bamford, D, Grimes, J
Format: Journal article
Language:English
Published: Public Library of Science 2011