Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets.

BACKGROUND: Increasing evidence suggests that individual isoforms of protein kinase C (PKC) play distinct roles in regulating platelet activation. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we focus on the role of two novel PKC isoforms, PKCdelta and PKCepsilon, in both mouse and human platelet...

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Bibliographic Details
Main Authors: Pears, C, Thornber, K, Auger, J, Hughes, C, Grygielska, B, Protty, M, Pearce, A, Watson, S
Format: Journal article
Language:English
Published: Public Library of Science 2008