Presentation of viral antigen controlled by a gene in the major histocompatibility complex.

We describe a mutant human cell line (LBL 721.174) that has lost a function required for presentation of intracellular viral antigens with class I molecules of the major histocompatibility complex (MHC), but retains the capacity to present defined epitopes as extracellular peptides. The cell also ha...

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Bibliographic Details
Main Authors: Cerundolo, V, Alexander, J, Anderson, K, Lamb, C, Cresswell, P, McMichael, A, Gotch, F, Townsend, A
Format: Journal article
Language:English
Published: 1990