Neuronal surface and glutamic acid decarboxylase autoantibodies in Nonparaneoplastic stiff person syndrome.

IMPORTANCE: High titers of autoantibodies to glutamic acid decarboxylase (GAD) are well documented in association with stiff person syndrome (SPS). Glutamic acid decarboxylase is the rate-limiting enzyme in the synthesis of γ-aminobutyric acid (GABA), and impaired function of GABAergic neurons has b...

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Bibliographic Details
Main Authors: Chang, T, Alexopoulos, H, Mcmenamin, M, Carvajal-González, A, Alexander, S, Deacon, R, Erdelyi, F, Szabó, G, Gabor, S, Lang, B, Blaes, F, Brown, P, Vincent, A
Format: Journal article
Language:English
Published: 2013