The p38 MAP kinase pathway as a therapeutic target in inflammatory disease.

The p38 MAPK signalling pathway plays an important role in inflammation and other physiological processes. Specific inhibitors of p38 alpha and beta MAPK block production of the major inflammatory cytokines (i.e. tumour necrosis factor-alpha and interleukin-1) and other proteins (e.g. cyclooxygenase...

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Détails bibliographiques
Auteur principal: Saklatvala, J
Format: Journal article
Langue:English
Publié: 2004