HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation

HIV-1 cure remains elusive with only one reported case a decade ago1,2. Termed the 'Berlin patient', the individual underwent two allogeneic haematopoietic stem-cell transplantation (allo-HSCT) procedures using a donor with a homozygous mutation in the HIV coreceptor CCR5 (CCR5Δ32/Δ32) to...

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Bibliographic Details
Main Authors: Gupta, R, Abdul-Jawad, S, McCoy, L, Mok, H, Peppa, D, Salgado, M, Martinez-Picado, J, Nijhuis, M, Wensing, A, Lee, H, Grant, P, Nastouli, E, Lambert, J, Pace, M, Salasc, F, Monit, C, Innes, A, Muir, L, Waters, L, Frater, J, Lever, A, Edwards, S, Gabriel, I, Olavarria, E
Format: Journal article
Language:English
Published: Springer Nature 2019