Predicting substrates for orphan solute carrier proteins using multi-omics datasets
Solute carriers (SLC) are integral membrane proteins responsible for transporting a wide variety of metabolites, signaling molecules and drugs across cellular membranes. Despite key roles in metabolism, signaling and pharmacology, around one third of SLC proteins are ‘orphans’ whose substrates are u...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2025
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