Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1

Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1

An immunosuppressive microenvironment causes poor tumor T cell infiltration and is associated with reduced patient overall survival in colorectal cancer. How to improve treatment responses in these tumors is still a challenge. Using an integrated screening approach to identify cancer-specific vulner...

Full description

Bibliographic Details
Main Authors: Beach, C, MacLean, D, Majorova, D, Melemenidis, S, Nambiar, DK, Kim, RK, Valbuena, GN, Guglietta, S, Krieg, C, Darvish-Damavandi, M, Suwa, T, Easton, A, Hillson, LV, McCulloch, AK, McMahon, RK, Pennel, K, Edwards, J, O'Cathail, SM, Roxburgh, CS, Domingo, E, Moon, EJ, Jiang, D, Jiang, Y, Zhang, Q, Koong, AC, Woodruff, TM, Graves, EE, Maughan, T, Buczacki, SJA, Stucki, M, Le, Q-T, Leedham, SJ, Giaccia, AJ, Olcina, MM
Format: Journal article
Language:English
Published: American Society for Clinical Investigation 2023

Similar Items