Increased limb involvement in murine collagen-induced arthritis following treatment with anti-interferon-gamma.
We have tested the effect of administering H22, a hamster neutralizing MoAb to murine interferon-gamma (IFN-gamma) in collagen-induced arthritis. Mice were immunized with human type II collagen in adjuvant on day 1 and boosted with soluble collagen on day 21. H22 was administered (250 micrograms, in...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
1993
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