Increased limb involvement in murine collagen-induced arthritis following treatment with anti-interferon-gamma.

Increased limb involvement in murine collagen-induced arthritis following treatment with anti-interferon-gamma.

We have tested the effect of administering H22, a hamster neutralizing MoAb to murine interferon-gamma (IFN-gamma) in collagen-induced arthritis. Mice were immunized with human type II collagen in adjuvant on day 1 and boosted with soluble collagen on day 21. H22 was administered (250 micrograms, in...

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Bibliographic Details
Main Authors:	Williams, R, Williams, D, Feldmann, M, Maini, R
Format:	Journal article
Language:	English
Published:	1993

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