Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

Hypertension affects more than one billion people worldwide. Here we identify 113 novel loci, reporting a total of 2,103 independent genetic signals (P < 5 × 10−8) from the largest single-stage blood pressure (BP) genome-wide association study to date (n = 1,028,980 European individuals). These a...

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Bibliographic Details
Main Authors:	Keaton, JM, Kamali, Z, Xie, T, Vaez, A, Williams, A, Goleva, SB, Ani, A, Evangelou, E, Hellwege, JN, Yengo, L, Young, WJ, Traylor, M, Giri, A, Zheng, Z, Zeng, J, Chasman, DI, Morris, AP, Caulfield, MJ, Hwang, S, Kooner, JS, Conen, D, Attia, JR, Morrison, AC, Loos, RJF, Goel, A, Watkins, H, van Duijn, CM
Format:	Journal article
Language:	English
Published:	Nature Research 2024

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

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