First births after preimplantation genetic diagnosis of structural chromosome abnormalities using comparative genomic hybridization and microarray analysis.

BACKGROUND: Balanced chromosomal rearrangements represent one of the most frequent indications for preimplantation genetic diagnosis (PGD). Although fluorescence in situ hybridization (FISH) has been successfully employed for diagnosis in such cases, this approach usually restricts assessment of th...

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Bibliographic Details
Main Authors: Alfarawati, S, Fragouli, E, Colls, P, Wells, D
Format: Journal article
Language:English
Published: 2011