Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malaria.

BACKGROUND: Artemisinin-based combination therapy (ACT) is currently recommended as first-line treatment for uncomplicated malaria, but of concern, it has been observed that the effectiveness of the main artemisinin derivative, artesunate, has been diminished due to parasite resistance. This reducti...

詳細記述

書誌詳細
主要な著者: Jamsen, K, Duffull, S, Tarning, J, Lindegardh, N, White, N, Simpson, J
フォーマット: Journal article
言語:English
出版事項: BioMed Central 2012