Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malaria.

BACKGROUND: Artemisinin-based combination therapy (ACT) is currently recommended as first-line treatment for uncomplicated malaria, but of concern, it has been observed that the effectiveness of the main artemisinin derivative, artesunate, has been diminished due to parasite resistance. This reducti...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jamsen, K, Duffull, S, Tarning, J, Lindegardh, N, White, N, Simpson, J
التنسيق: Journal article
اللغة:English
منشور في: BioMed Central 2012