Optimal designs for population pharmacokinetic studies of the partner drugs co-administered with artemisinin derivatives in patients with uncomplicated falciparum malaria.
BACKGROUND: Artemisinin-based combination therapy (ACT) is currently recommended as first-line treatment for uncomplicated malaria, but of concern, it has been observed that the effectiveness of the main artemisinin derivative, artesunate, has been diminished due to parasite resistance. This reducti...
Những tác giả chính: | , , , , , |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
BioMed Central
2012
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