Elucidating the functional role and therapeutic potential of La-related protein 1B (LARP1B) in cancer and its interplay with other LARP family members

Elucidating the functional role and therapeutic potential of La-related protein 1B (LARP1B) in cancer and its interplay with other LARP family members

<p>RNA binding proteins (RBPs) are indispensable regulators of gene expression with a growing body of evidence demonstrating their role in cellular acquisition of the hallmarks of cancer. By regulating the expression of hallmark regulatory genes, RBPs mediate key cancer phenotypes including su...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter:	Nawaz, A
Andre forfattere:	Blagden, S
Format:	Thesis
Sprog:	English
Udgivet:	2023

Lignende værker

The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
af: Jennifer C. Coleman, et al.
Udgivet: (2024-04-01)

Interplay between LARP1 and MYC - a two-way regulation?
af: Fellermeyer, M
Udgivet: (2018)

Controversies around the function of LARP1
af: Berman, AJ, et al.
Udgivet: (2020)

The RNA-binding protein LARP1 is a cancer therapeutic target
af: Ghazaly, E, et al.
Udgivet: (2017)

Genome-wide investigation of the LARP gene family: focus on functional identification and transcriptome profiling of ZmLARP6c1 in maize pollen
af: Xiaoqin Xiang, et al.
Udgivet: (2024-04-01)

LARP3, LARP7, and MePCE are involved in the early stage of human telomerase RNA biogenesis
af: Tsai-Ling Kao, et al.
Udgivet: (2024-07-01)

LARP7 family proteins have conserved function in telomerase assembly
af: Laura C. Collopy, et al.
Udgivet: (2018-02-01)

Loss of LARP4B, an early event in the tumorigenesis of brain cancer?
af: Blagden, S, et al.
Udgivet: (2016)

LARP1 haploinsufficiency is associated with an autosomal dominant neurodevelopmental disorder
af: James Chettle, et al.
Udgivet: (2024-10-01)

Up-regulation of circ_LARP4 suppresses cell proliferation and migration in ovarian cancer by regulating miR-513b-5p/LARP4 axis
af: Wumei Lin, et al.
Udgivet: (2020-01-01)

The role of LARP1 in communication between ovarian tumours and their immune microenvironment
af: Gross, F
Udgivet: (2022)

The RNA-binding protein LARP1 is dispensable for pancreatic β-cell function and mass
af: Joao Pedro Werneck-de-Castro, et al.
Udgivet: (2021-01-01)

Playing at the Margins: Colonizing Fictions in New England Larp
af: Zoë Antoinette Eddy
Udgivet: (2020-12-01)

A God-Tier LARP? QAnon as Conspiracy Fictioning
af: Daniël de Zeeuw, et al.
Udgivet: (2023-03-01)

LARP4 mRNA codon-tRNA match contributes to LARP4 activity for ribosomal protein mRNA poly(A) tail length protection
af: Sandy Mattijssen, et al.
Udgivet: (2017-09-01)

LARP1 post-transcriptionally regulates mTOR and contributes to cancer progression
af: Blagden, S, et al.
Udgivet: (2015)

Targeting the oncogenic LARP1/DKK4/β‐catenin axis in hepatoblastoma
af: Fuda Xie, et al.
Udgivet: (2023-06-01)

Monsters Escaping the Screen: Embodied Narratives of LARPS and Zombie Walks
af: Kristina Stenström
Udgivet: (2017-11-01)

A Mammalian Conserved Circular RNA CircLARP1B Regulates Hepatocellular Carcinoma Metastasis and Lipid Metabolism
af: Jingxin Li, et al.
Udgivet: (2024-01-01)

Crystal Structure of a Variant PAM2 Motif of LARP4B Bound to the MLLE Domain of PABPC1
af: Clemens Grimm, et al.
Udgivet: (2020-06-01)

The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer
af: Hopkins, T, et al.
Udgivet: (2015)

Induction of LARP1B under endoplasmic reticulum stress and its regulatory role in proliferation of esophageal squamous cell carcinoma
af: Xia Yang, et al.
Udgivet: (2024-12-01)

Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1
af: Guennadi Kozlov, et al.
Udgivet: (2024-12-01)

LARP4B promotes hepatocellular carcinoma progression and impairs sorafenib efficacy by activating SPINK1-mediated EGFR pathway
af: Chuanxu Wang, et al.
Udgivet: (2024-05-01)

LARP7 is required for sex chromosome silencing during meiosis in mice.
af: Yukiko Tando, et al.
Udgivet: (2024-01-01)

O LARP COMO FERRAMENTA DE TRABALHO DO ATOR/PERFORMER
af: Thiago Vieira Borges da Rosa, et al.
Udgivet: (2019-08-01)

Impaired telomere maintenance in Alazami syndrome patients with LARP7 deficiency
af: Brody Holohan, et al.
Udgivet: (2016-10-01)

Comparative analysis of the LARP1 C-terminal DM15 region through Coelomate evolution
af: Elaine Nguyen, et al.
Udgivet: (2024-01-01)

LARP1 knockdown inhibits cultured gastric carcinoma cell cycle progression and metastatic behavior
af: Liu Xin, et al.
Udgivet: (2024-01-01)

Entrepreneurial and social significance of larps: A case study of the Kuńkowce Fantasy Village
af: Krzysztof Sala
Udgivet: (2023-06-01)

Assessing Risk Acceptability and Tolerability in Italian Tunnels with the Quantum Gu@larp Model
af: Massimo Guarascio, et al.
Udgivet: (2023-12-01)

Interaction of LARP4 to filamin A mechanosensing domain regulates cell migrations
af: Zhenfeng Mao, et al.
Udgivet: (2023-04-01)

Parallel global profiling of plant TOR dynamics reveals a conserved role for LARP1 in translation
af: M Regina Scarpin, et al.
Udgivet: (2020-10-01)

The La-related protein PsLARP4_5 is crucial for zoospore production and pathogenicity in Phytophthora sojae
af: Can Zhang, et al.
Udgivet: (2023-11-01)

LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs
af: Sungki Hong, et al.
Udgivet: (2017-06-01)

LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis
af: Xiaodan Ji, et al.
Udgivet: (2014-07-01)

Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane.
af: Hao Wang, et al.
Udgivet: (2014-01-01)

Telocinobufagin suppresses malignant metastasis of undifferentiated thyroid carcinoma via modulation of the LARP1‐mTOR pathway
af: Li‐Zhi Qiang, et al.
Udgivet: (2025-03-01)

La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs
af: Lahr, RM, et al.
Udgivet: (2017)

La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs
af: Roni M Lahr, et al.
Udgivet: (2017-04-01)