Expression-System-Dependent Modulation of HIV-1 Envelope Glycoprotein Antigenicity and Immunogenicity

Recombinant expression systems differ in the type of glycosylation they impart on expressed antigens such as the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins, potentially affecting their biological properties. We performed head-to-head antigenic, immunogenic and molecular profi...

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Bibliographic Details
Main Authors: Kong, L, Sheppard, N, Stewart-Jones, G, Robson, C, Chen, H, Xu, X, Krashias, G, Bonomelli, C, Scanlan, C, Kwong, P, Jeffs, SA, Jones, I, Sattentau, Q
Format: Journal article
Language:English
Published: 2010