The ambiguous role of NKX2-5 mutations in thyroid dysgenesis

The ambiguous role of NKX2-5 mutations in thyroid dysgenesis

NKX2-5 is a homeodomain-containing transcription factor implied in both heart and thyroid development. Numerous mutations in NKX2-5 have been reported in individuals with congenital heart disease (CHD), but recently a select few have been associated with thyroid dysgenesis, among which the p.A119S v...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Van Engelen, K, Mommersteeg, M, Baars, M, Lam, J, Ilgun, A, Van Trotsenburg, A, Smets, A, Christoffels, V, Mulder, B, Postma, A
स्वरूप: Journal article
भाषा:English
प्रकाशित: Public Library of Science 2012

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