Asymmetric synthesis of d-fagomine and its diastereoisomers
A divergent strategy for the asymmetric syntheses of d-fagomine and three of its diastereoisomers has been developed. The diastereoselective conjugate addition of an enantiopure lithium amide to an α,β-unsaturated ester was used as the key step to install the correct configuration required for the C...
Hauptverfasser: | Davies, S, Fletcher, A, Kennedy, M, Roberts, P, Thomson, J |
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Format: | Journal article |
Veröffentlicht: |
Elsevier
2018
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