Asymmetric synthesis of d-fagomine and its diastereoisomers

Asymmetric synthesis of d-fagomine and its diastereoisomers

A divergent strategy for the asymmetric syntheses of d-fagomine and three of its diastereoisomers has been developed. The diastereoselective conjugate addition of an enantiopure lithium amide to an α,β-unsaturated ester was used as the key step to install the correct configuration required for the C...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Davies, S, Fletcher, A, Kennedy, M, Roberts, P, Thomson, J
Формат:	Journal article
Хэвлэсэн:	Elsevier 2018

Ижил төстэй зүйлс

Asymmetric syntheses of fagomine and its stereoisomers
-н: Davies, S, зэрэг
Хэвлэсэн: (2019)

Asymmetric syntheses of (-)-3-epi-Fagomine, (2R,3S,4R)-dihydroxypipecolic acid, and several polyhydroxylated homopipecolic acids.
-н: Csatayová, K, зэрэг
Хэвлэсэн: (2014)

Ammonium-directed dihydroxylation: metal-free synthesis of the diastereoisomers of 3-aminocyclohexane-1,2-diol.
-н: Aciro, C, зэрэг
Хэвлэсэн: (2008)

Synthesis of Optically Pure Diastereoisomers of Reduced Folates
-н: Groehn V., зэрэг
Хэвлэсэн: (1999-08-01)

Eubiotic effect of buckwheat d-fagomine in healthy rats
-н: Mercè Hereu, зэрэг
Хэвлэсэн: (2018-11-01)

Three step synthesis of single diastereoisomers of the vicinal trifluoro motif
-н: Vincent A. Brunet, зэрэг
Хэвлэсэн: (2009-11-01)

Asymmetric synthesis of the tetraponerine alkaloids
-н: Davies, S, зэрэг
Хэвлэсэн: (2017)

Asymmetric synthesis of (-)-(R)-sitagliptin
-н: Davies, S, зэрэг
Хэвлэсэн: (2012)

Asymmetric synthesis of (-)-(R)-sitagliptin
-н: Davies, S, зэрэг
Хэвлэсэн: (2012)

Asymmetric synthesis of (-)-(R)-sitagliptin
-н: Davies, S, зэрэг
Хэвлэсэн: (2012)

Asymmetric synthesis of (-)-martinellic acid.
-н: Davies, S, зэрэг
Хэвлэсэн: (2013)

Polysubstituted piperidines via iodolactonization: application to the asymmetric synthesis of (+)-pseudodistomin D.
-н: Davies, S, зэрэг
Хэвлэсэн: (2012)

An efficient asymmetric synthesis of (-)-lupinine.
-н: Davies, S, зэрэг
Хэвлэсэн: (2014)

Asymmetric synthesis of beta-fluoroaryl-beta-amino acids
-н: Davies, S, зэрэг
Хэвлэсэн: (2012)

(-)-Pseudodistomin E: First asymmetric synthesis and absolute configuration assignment
-н: Davies, S, зэрэг
Хэвлэсэн: (2017)

Asymmetric synthesis of pyrrolizidines, indolizidines and quinolizidines via a double reductive cyclisation protocol
-н: Davies, S, зэрэг
Хэвлэсэн: (2017)

Conformational diastereoisomers of PPh3 coordinated to stereogenic metal centres as molecular optical switches
-н: Ayscough, A, зэрэг
Хэвлэсэн: (2001)

Asymmetric synthesis of (-)-(1R,7aS)-absouline
-н: Davies, S, зэрэг
Хэвлэсэн: (2013)

Asymmetric synthesis of (-)-(1R,7aS)-absouline
-н: Davies, S, зэрэг
Хэвлэсэн: (2013)

Mode of Antibacterial Action of Tomatidine C3-Diastereoisomers
-н: Jean-Philippe Langlois, зэрэг
Хэвлэсэн: (2024-01-01)

Trading N and O. Part 4: Asymmetric synthesis of syn-β-substituted-α-amino acids
-н: Davies, S, зэрэг
Хэвлэсэн: (2018)

Asymmetric synthesis of (-)-(S,S)-homaline
-н: Davies, S, зэрэг
Хэвлэсэн: (2012)

Asymmetric synthesis of (-)-(S,S)-homaline
-н: Davies, S, зэрэг
Хэвлэсэн: (2012)

Asymmetric synthesis of (-)-codonopsinine
-н: Davies, S, зэрэг
Хэвлэсэн: (2011)

Asymmetric synthesis of (-)-codonopsinine
-н: Davies, S, зэрэг
Хэвлэсэн: (2011)

The asymmetric synthesis of (S,S)-methylphenidate hydrochloride via ring-opening of an enantiopure aziridinium intermediate with phenylmagnesium bromide
-н: Davies, S, зэрэг
Хэвлэсэн: (2019)

Asymmetric synthesis of tetrahydrolipstatin and valilactone
-н: Case-Green, S, зэрэг
Хэвлэсэн: (2008)

Concise and highly selective asymmetric synthesis of acosamine from sorbic acid
-н: Bagal, S, зэрэг
Хэвлэсэн: (2011)

Concise and highly selective asymmetric synthesis of acosamine from sorbic acid
-н: Bagal, S, зэрэг
Хэвлэсэн: (2011)

Concise and highly selective asymmetric synthesis of acosamine from sorbic acid
-н: Bagal, S, зэрэг
Хэвлэсэн: (2011)

Asymmetric syntheses of (-)-isoretronecanol and (-)-trachelantamidine
-н: Brambilla, M, зэрэг
Хэвлэсэн: (2014)

Inhibition of Lysozyme Amyloid Fibrillation by Silybin Diastereoisomers: The Effects of Stereochemistry
-н: Xuanyu Chen, зэрэг
Хэвлэсэн: (2021-01-01)

Pharmacokinetics of pure silybin diastereoisomers and identification of their metabolites in rat plasma
-н: Petr Marhol, зэрэг
Хэвлэсэн: (2015-04-01)

Asymmetric synthesis of the marine alkaloid (-)-(S)-nakinadine C
-н: Davies, S, зэрэг
Хэвлэсэн: (2013)

(-)-(S)-Nakinadine B: first asymmetric synthesis.
-н: Davies, S, зэрэг
Хэвлэсэн: (2012)

Asymmetric syntheses of (- )-hastanecine, (- )-turneforcidine and (- )-platynecine
-н: Davies, S, зэрэг
Хэвлэсэн: (2016)

(-)-(2S,3R,Z)-Nakinadine A: first asymmetric synthesis and absolute configuration assignment.
-н: Davies, S, зэрэг
Хэвлэсэн: (2014)

Asymmetric synthesis of the allocolchicinoid natural product N-acetylcolchinol methyl ether (suhailamine), solid state and solution phase conformational analysis
-н: Davies, S, зэрэг
Хэвлэсэн: (2019)

Asymmetric syntheses of the methyl glycosides of 2-deoxy-2-aminohexoses: D-allosamine, D-mannosamine, D-idosamine and D-talosamine
-н: Davies, S, зэрэг
Хэвлэсэн: (2014)

Asymmetric Synthesis of Piperidines and Octahydroindolizines
-н: Davies, S, зэрэг
Хэвлэсэн: (2010)