Asymmetric synthesis of d-fagomine and its diastereoisomers

A divergent strategy for the asymmetric syntheses of d-fagomine and three of its diastereoisomers has been developed. The diastereoselective conjugate addition of an enantiopure lithium amide to an α,β-unsaturated ester was used as the key step to install the correct configuration required for the C...

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Những tác giả chính: Davies, S, Fletcher, A, Kennedy, M, Roberts, P, Thomson, J
Định dạng: Journal article
Được phát hành: Elsevier 2018