Mice with an N-ethyl-N-nitrosourea (ENU) induced Tyr209Asn mutation in natriuretic peptide receptor 3 (NPR3) provide a model for kyphosis associated with activation of the MAPK signaling pathway

Mice with an N-ethyl-N-nitrosourea (ENU) induced Tyr209Asn mutation in natriuretic peptide receptor 3 (NPR3) provide a model for kyphosis associated with activation of the MAPK signaling pathway

Non-syndromic kyphosis is a common disorder that is associated with significant morbidity and has a strong genetic involvement; however, the causative genes remain to be identified, as such studies are hampered by genetic heterogeneity, small families and various modes of inheritance. To overcome th...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Esapa, C, Piret, S, Nesbit, M, Loh, N, Thomas, G, Croucher, P, Brown, M, Brown, S, Cox, R, Thakker, R
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Public Library of Science 2016

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